At TransViragen we offer a full range of services related to the production of knockout and conditional knockout mice, including CRISPR targeting in embryos, ES cell gene targeting, ES cell injection, animal breeding, genotyping, and phenotyping.

The time required to generate a knockout or conditional knockout mouse varies depending on the specific gene and the complexity of the targeting strategy. The process can take as little as 6 months for straightforward knockout projects, while timelines may extend to 12 months or longer for more complex models or projects requiring additional breeding steps.

The costs associated with generating a knockout or conditional knockout mouse can vary depending on the specific gene, the complexity of the targeting strategy, and the number of animals required. We typically provide custom quotes for each project based on these factors.

Knockout and conditional knockout strategies can be used to target virtually any gene of interest, including those involved in disease development, drug metabolism, and developmental biology.

We offer C57BL/6J, C57BL/6N, FVB, Balb/c, NOD, 129 as background strains. Other custom strains are also available upon request.